歐秀中 Hsiu-Chung Ou
狀態 專任師資
姓名 歐秀中 Hsiu-Chung Ou
電子郵件 ouhc0822@gmail.com
職稱 教授
研究室 I406
校內分機 6550; 1879
學歷
中山醫學大學生化暨生物科技研究所博士
陽明大學生命科學學院神經科學碩士
中山醫學大學復健醫學學士
經歷
亞洲大學 物理治療學系 系主任
亞洲大學職能治療系副教授
加拿大亞伯達大學物理治療研究所訪問研究
中國醫藥大學物理治療學系副教授
專長
心血管疾病致病分子機轉
腦中風致病分子機轉
糖尿病及動脈硬化致病分子機轉
請益時間 歐秀中.pdf
教師歷程檔案 http://research.asia.edu.tw/TchEportfolio/index_1/ouhc99#
現職 亞洲大學物理治療學系 主任
年度 論文名稱
2021 古昌文(Ku, Chang-Wen)、何宗融(Ho, Tsung-Jung)、黃志揚(Huang, Chih-Yang)、朱培銘(Chu, Pei-Ming)、歐秀中(Hsiu-chung Ou)、謝佩伶(Hsieh, Pei-Ling), Cordycepin Attenuates Palmitic Acid-Induced Inflammation and Apoptosis of Vascular Endothelial Cells through Mediating PI3K/Akt/eNOS Signaling Pathway, AMERICAN JOURNAL OF CHINESE MEDICINE
2021 歐秀中(Hsiu-chung Ou)、朱培銘(Chu, Pei-Ming)、Yu?Ting Huang、Hui?Ching Cheng、Wan?Ching Chou、Hsin?Lun Yang、陳?儀(CHEN, HSIU-I)、蔡昆霖(Kun?Ling Tsa), Low-level laser prevents doxorubicin-induced skeletal muscle atrophy by modulating AMPK/SIRT1/PCG-1α-mediated mitochondrial function, apoptosis and up-regulation of pro-inflammatory responses, Cell and Bioscience
2021 古昌文(Chang-Wen Ku)、Cecilia Hsuan Day、歐秀中(Hsiu-chung Ou)、何宗融(Tsung-Jung Ho)、Ray-Jade Chen、Velmurugan Bharath Kumar,、Wen-Yuan Lin、黃志揚(Huang, Chih-Yang), The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats, Open Life Sciences
2021 林美儀(Lin, Mei-Yi)、Wan-Ting Cheng、Hui-Ching Cheng、Wan-Ching Chou、陳?儀(Chen, Hsiu-I)、歐秀中(Hsiu-chung Ou)、蔡昆霖*, Baicalin Enhances Chemosensitivity to Doxorubicin in Breast Cancer Cells via Upregulation of Oxidative Stress-Mediated Mitochondria-Dependent Apoptosis, Antioxidants (Basel)
2021 白培英、Wan-Ching Chou、Shih-Hung Chan、Shu-Yih Wu、陳?儀(CHEN, HSIU-I)、李啟文(Li Chi Wen)、Pei-Ling Hsieh、Pei-Ming Chu、Yu-An Chen、歐秀中(Hsiu-chung Ou)*, Epigallocatechin Gallate Reduces Homocysteine-Caused Oxidative Damages through Modulation SIRT1/AMPK Pathway in Endothelial Cells, AMERICAN JOURNAL OF CHINESE MEDICINE
2020 陳?儀(Hsiu-I. Chen)、Wei-Syun Hu、Meng-Yu Hung、歐秀中(Hsiu-chung Ou)、黃素華(Su-Hua Huang)、Pei-Tzu Hsu、Cecilia-Hsuan Day、Kuan-Ho Lin、Vijaya P Viswanadha(Vijaya P Viswanadha)*、郭薇雯(Wei-Wen Kuo)、歐秀中(Hsiu-chung Ou), Protective Effects of Luteolin Against Oxidative Stress and Mitochondrial Dysfunction in Endothelial Cells, NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, vol.30 no.6 pp.1032-1043
2020 Lu CH、歐秀中(Hsiu-chung Ou)、Day CH、陳?儀(Chen HI)、白培英(Pai PY)、Lee CY、Chen RJ、Chang RL、Vijaya P. Viswanadha、黃志揚(Huang, Chih-Yang)*、歐秀中(Hsiu-chung Ou), Deep Sea Minerals Ameliorate Diabetic-Induced Inflammation via Inhibition of TNFα Signaling Pathways, ENVIRONMENTAL TOXICOLOGY, vol.35
2020 Hsiu-I Chen、歐秀中、Chung-Yu Chen、Shao-Hong Y、鄭秀敏(Shiu-Min Cheng)、Xu-Bo Wu、李信達(Shin-Da Lee), Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model, AMERICAN JOURNAL OF CHINESE MEDICINE
2020 Hsiu-I Chen、歐秀中(Hsiu-chung Ou), Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model, The American journal of Chinese medicine, vol.48 no.2 pp.373-390
2020 Shiu-Min Cheng、歐秀中(Hsiu-chung Ou), Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain, The American journal of Chinese medicine, vol.48 no.2 pp.391-406
2019 Lu CH(Lu CH)*、Shen CY、Hsieh DJ、Lee CY、Chang RL、Ju DT、白培英(Pai PY)、Viswanadha VP、歐秀中(Ou Hsiu-Chung)、黃志揚(Huang CY), Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts., Journal of applied physiology, vol.127 no.2 pp.356-364
2019 歐秀中、Wan-Ching Chou、洪菁霞(Ching-Hsia Hung)、朱培銘(Pei-Ming Chu)、謝珮伶(Pei-Ling Hsieh)、Shih-Hung Chan、蔡昆霖(Kun-Ling Tsai)*, Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway, ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
2019 Pandey S(Pandey S)*, Luteolin: a natural flavonoid enhances the longevity of HUVECs against oxidative stress by modulating AMPK/PKC pathway., The American journal of Chinese medicine, vol.47 no.3 pp.541-557
2019 歐秀中(Ou, Hsiu-Chung)、Wan-Ching Chou、Pei-Ming Chu、Pei-Ling Hsieh、洪菁霞(Ching-Hsia Hung)、蔡昆霖(Kun-Ling Tsai)*, Fucoxanthin Protects against oxLDL-Induced Endothelial Damage via Activating the AMPK-Akt-CREB-PGC1α Pathway, MOLECULAR NUTRITION & FOOD RESEARCH
2018 蔡昆霖(Tsai, Kun-Ling)、洪菁霞(Hung, Ching-Hsia)、詹世鴻(Chan, Shih-Hung)、謝佩伶(Hsieh, Pei-Ling)、歐秀中(Ou, Hsiu-Chung)、鄭詠馨(Cheng, Yung-Hsin)、朱培銘(Chu, Pei-Ming)*, Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.62 no.11 pp.e1700928-
2018 Tsai KL(Tsai KL)*, Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells. Mol Nutr Food Res, IRISH JOURNAL OF AGRICULTURAL AND FOOD RESEARCH, vol.62 no.11 pp.e1700928-
2017 Wen SY(Wen SY)*, Viswanadha VP, Kuo WW, Huang CY. Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis. PLoS One., PLoS One, vol.12 no.6 pp.e0179492-
2017 Huang YT(Huang YT)*, Diallyl trisulfide & diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats., PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.3 pp.402-410
2017 Wen SY(Wen SY)*, Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis, PLoS One, vol.12 no.6 pp.e1709492-
2014 Lee CH,(Lee CH,)*, Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway., INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.15 no.6 pp.10334-10349
2013 Cheng SM(Cheng SM)*, Exercise training enhances cardiac IGFI-R/PI3K/Akt and Bcl-2 family associated pro-survival pathways in streptozotocin-induced diabetic rats, INTERNATIONAL JOURNAL OF CARDIOLOGY, vol.167 no.2 pp.478-485
2013 Hsieh YL,(Hsieh YL,)*, Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism, PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.2 pp.274-285
2012 Kun-Ling Tsai(Kun-Ling Tsai)*, Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway, MOLECULAR NUTRITION & FOOD RESEARCH, vol.55 no.2 pp.227-240
2012 Tsai KL(Tsai KL)*, A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways., JOURNAL OF VASCULAR SURGERY, vol.23 no.5 pp.458-468
2012 Lee WJ,( Lee WJ,)*, Aspirin inhibits resistin-induced endothelial dysfunction: roles of ROS and Akt/eNOS/NO signaling pathway., JOURNAL OF VASCULAR SURGERY, vol.55 no.4 pp.1104-1115
2011 Tsai KL(Tsai KL)*, Green tea epigallocatechin-3-gallate (EGCG) reduced endothelial cells dysfunction and adhesion molecule expression induced by oxidized-LDL., BIOCHEMICAL PHARMACOLOGY, vol.82 no.12 pp.1807-1821
2011 Chen JY(Chen JY)*, Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways., BIOCHEMICAL PHARMACOLOGY, vol.674 no.2-3 pp.227-233
2010 Tsai KL(Tsai KL)*, EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling, EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, vol.108 no.6 pp.1745-1756
2007 Hsiu-Chung Ou(Hsiu-Chung Ou)*, Protective effects of magnolol against oxidized LDL-induced cytotoxicity in endothelial cells., JOURNAL OF VASCULAR SURGERY, vol.81 no.6 pp.421-432
2006 Hsiu-Chung Ou, Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells., CLINICA CHIMICA ACTA, vol.2006 no.364 pp.196-204
2006 Sheu WH, Rosiglitazone inhibits endothelial proliferation and angiogenesis., LIFE SCIENCES, vol.2006 no.364 pp.196-204
2005 Lee IT, Hypercholesterolemia, not metabolic syndrome, related to adhesion of monocytes to cultured endothelium in nondiabetic subjects. Metabolism., METABOLISM-CLINICAL AND EXPERIMENTAL, vol.2005 no.54 pp.1467-1471
2005 Chi-Feng Hung(Chi-Feng Hung)*, (-)Epigallocatechin-3-gallate (EGCG), a Polyphenolic Compound in Green Tea, Protetcs Against Endothelial Cells Inflammation via Oxidized LDL., JOURNAL OF CELLULAR BIOCHEMISTRY, vol.96 no.1 pp.183-197
2005 Tsai KL(Tsai KL)*, Solanum Lyratum Thumb Prevent Oxidized Low-density Lipoprotein-induced Endothelial Dysfunction., Medicine & Science in Sports & Exercise, vol.41 no.5 pp.172-
2005 Huang HM, Protective Effect of -Keto--Methyl-nValeric Acid on BV-2 Microglia under Hypoxia or Oxidative Stress, Annals of the New York Academy of Sciences
2004 Huang HM, alpha-keto-beta-methyl- n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores., FREE RADICAL BIOLOGY AND MEDICINE, vol.2004 no.37 pp.1779-1789
2004 Shen CC, Protective effect of nicotinamide on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation., JOURNAL OF BIOMEDICAL SCIENCE, vol.2004 no.11 pp.472-481
2002 Huang HM, Apolipoprotein E polymorphism in various dementias in Taiwan Chinese population., JOURNAL OF NEURAL TRANSMISSION, vol.2002 no.109 pp.1415-21
2002 Mei-Jen Wang, Silymarin protects dopaminergic neurons against lipopolysaccharide- induced neurotoxicity by inhibiting microglia activation., EUROPEAN JOURNAL OF NEUROSCIENCE, vol.2002 no.16 pp.2103-2112
2000 Huang HM, Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons., LIFE SCIENCES, vol.2000 no.66 pp.1879-1892
2000 Huang HM, Amyloid beta peptide impaired carbachol but not glutamate-mediated phosphoinositide pathways in cultured rat cortical neurons, CHINESE MEDICAL JOURNAL, vol.2000 no.25 pp.303-312
2000 Kuo JS, Differential alteration of catecholamine release during chemical hypoxia is correlated with cell toxicity and is blocked by protein kinase C inhibitors in PC12 cells., JOURNAL OF CELLULAR BIOCHEMISTRY, vol.2000 no.79 pp.191-201
發表日期 論文名稱
2011.04 歐秀中(Hsiu-chung Ou), 2nd National Obesity Summit, Montreal, Canada
2010.08 歐秀中(Hsiu-chung Ou), Eighth Annual Scientific Sessions: Metabolic Signaling in the Cardiovascular System, Alberta, Canada
2010.04 歐秀中(Hsiu-chung Ou), Experimental Biology, 2010, Califonia, USA
2009.05 蔡昆霖、歐秀中(Hsiu-chung Ou), ACSM's Annual Meeting, Seattle, USA
2008.06 歐秀中(Hsiu-chung Ou), Society for Heart & Vascular Metabolism, Boston, USA
計畫名稱 參與人 計畫期間
低能量電射改善化療藥物造成肌肉衰弱之效果探討:從分子機轉到動物研究 (109-2635-B-468-001) 歐秀中(Hsiu-chung Ou)、蔡昆霖(Kun-Ling Tsai) 2020.08 ~ 2021.07
The antiatherogenic effects of sesamin in vitro and in vivo 2009.08 ~ 2012.07
Effects of polyphenolic compounds and exercise preconditioning protect against injury in a cerebral ischemia/reperfusion model in rat 2008.08 ~ 2009.07
Protective effect of sesamin on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation 2007.08 ~ 2008.07
Effects of ginkgo on oxLDL-promoted interaction between monocyte and vascular endothelium: regulation of redox status, adhesion molecules, and trans-endothelial migration (National Science Council) 2006.08 ~ 2007.07
獎項名稱 頒獎單位
中國醫藥大學健康照護學院研究傑出獎 請選擇
中國醫藥大學健康照護學院研究傑出獎