| 姓名 | 欧秀中 Hsiu-Chung Ou |
|---|---|
| 电子邮件 | |
| 职称 | 教授 |
| 学历 |
中山医学大学生化暨生物科技研究所博士 阳明大学生命科学学院神经科学硕士 中山医学大学复健医学学士 |
| 经历 |
亚洲大学 物理治疗学系 系主任 亚洲大学职能治疗系副教授 加拿大亚伯达大学物理治疗研究所访问研究 中国医药大学物理治疗学系副教授 |
| 专长 |
心血管疾病致病分子机转 脑中风致病分子机转 糖尿病及动脉硬化致病分子机转 |
| 教师历程档案 | http://research.asia.edu.tw/TchEportfolio/index_1/ouhc99# |
| 现职 | 亚洲大学物理治疗学系 主任 |
| 教师历程档案 | http://research.asia.edu.tw/TchEportfolio/index_1/ouhc99# |
| 年度 | 论文名称 |
|---|---|
| 2023 | 邱灿宏(Tsan-Hung Chiu)、古昌文(Chang-Wen Ku)、何宗荣(Tsung-Jung Ho)、蔡昆霖(Kun-Ling Tsai)、杨奕彤(Yi-Dung Yang)、欧秀中(Hsiu-chung Ou)*、陈?仪(CHEN, HSIU-I), Schisanhenol ameliorates oxLDL-caused endothelial dysfunction by inhibiting LOX-1 signaling, ENVIRONMENTAL TOXICOLOGY, 2023 |
| 2022 | Wang SH、Tsai KL、Chou WC、Cheng HC、Huang YT、欧秀中(Hsiu-chung Ou)、Chang YC(Chang YC)*, Quercetin Mitigates Cisplatin-Induced Oxidative Damage and Apoptosis in Cardiomyocytes through Nrf2/HO-1 Signaling Pathway, AMERICAN JOURNAL OF CHINESE MEDICINE, 2022 |
| 2021 | 白培英、Wan-Ching Chou、Shih-Hung Chan、Shu-Yih Wu、陈?仪(CHEN, HSIU-I)、李启文(Li Chi Wen)、Pei-Ling Hsieh、Pei-Ming Chu、Yu-An Chen、欧秀中(Hsiu-chung Ou)*, Epigallocatechin Gallate Reduces Homocysteine-Caused Oxidative Damages through Modulation SIRT1/AMPK Pathway in Endothelial Cells, AMERICAN JOURNAL OF CHINESE MEDICINE, 2021 |
| 2021 | 林美仪(Lin, Mei-Yi)、Wan-Ting Cheng、Hui-Ching Cheng、Wan-Ching Chou、陈?仪(Chen, Hsiu-I)、欧秀中(Hsiu-chung Ou)、蔡昆霖*, Baicalin Enhances Chemosensitivity to Doxorubicin in Breast Cancer Cells via Upregulation of Oxidative Stress-Mediated Mitochondria-Dependent Apoptosis, Antioxidants (Basel), 2021 |
| 2021 | 古昌文(Chang-Wen Ku)、Cecilia Hsuan Day、欧秀中(Hsiu-chung Ou)、何宗融(Tsung-Jung Ho)、Ray-Jade Chen、Velmurugan Bharath Kumar,、Wen-Yuan Lin、黄志扬(Huang, Chih-Yang), The molecular mechanisms underlying arecoline-induced cardiac fibrosis in rats, Open Life Sciences, 2021 |
| 2021 | 欧秀中(Hsiu-chung Ou)、朱培铭(Chu, Pei-Ming)、Yu?Ting Huang、Hui?Ching Cheng、Wan?Ching Chou、Hsin?Lun Yang、陈?仪(CHEN, HSIU-I)、蔡昆霖(Kun?Ling Tsa), Low-level laser prevents doxorubicin-induced skeletal muscle atrophy by modulating AMPK/SIRT1/PCG-1α-mediated mitochondrial function, apoptosis and up-regulation of pro-inflammatory responses, Cell and Bioscience, 2021 |
| 2021 | 古昌文(Ku, Chang-Wen)、何宗融(Ho, Tsung-Jung)、黄志扬(Huang, Chih-Yang)、朱培铭(Chu, Pei-Ming)、欧秀中(Hsiu-chung Ou)、谢佩伶(Hsieh, Pei-Ling), Cordycepin Attenuates Palmitic Acid-Induced Inflammation and Apoptosis of Vascular Endothelial Cells through Mediating PI3K/Akt/eNOS Signaling Pathway, AMERICAN JOURNAL OF CHINESE MEDICINE, 2021 |
| 2020 | Shiu-Min Cheng、欧秀中(Hsiu-chung Ou), Anti-Apoptotic Effects of Diosgenin in D-Galactose-Induced Aging Brain, The American journal of Chinese medicine, vol.48 no.2 pp.391-406, 2020 |
| 2020 | Hsiu-I Chen、欧秀中(Hsiu-chung Ou), Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model, The American journal of Chinese medicine, vol.48 no.2 pp.373-390, 2020 |
| 2020 | Hsiu-I Chen、欧秀中、Chung-Yu Chen、Shao-Hong Y、郑秀敏(Shiu-Min Cheng)、Xu-Bo Wu、李信达(Shin-Da Lee), Neuroprotective Effect of Rhodiola crenulata in D-Galactose-Induced Aging Model, AMERICAN JOURNAL OF CHINESE MEDICINE, 2020 |
| 2020 | Lu CH、欧秀中(Hsiu-chung Ou)、Day CH、陈?仪(Chen HI)、白培英(Pai PY)、Lee CY、Chen RJ、Chang RL、Vijaya P. Viswanadha、黄志扬(Huang, Chih-Yang)*、欧秀中(Hsiu-chung Ou), Deep Sea Minerals Ameliorate Diabetic-Induced Inflammation via Inhibition of TNFα Signaling Pathways, ENVIRONMENTAL TOXICOLOGY, vol.35, 2020 |
| 2020 | 陈?仪(Hsiu-I. Chen)、Wei-Syun Hu、Meng-Yu Hung、欧秀中(Hsiu-chung Ou)、黄素华(Su-Hua Huang)、Pei-Tzu Hsu、Cecilia-Hsuan Day、Kuan-Ho Lin、Vijaya P Viswanadha(Vijaya P Viswanadha)*、郭薇雯(Wei-Wen Kuo)、欧秀中(Hsiu-chung Ou), Protective Effects of Luteolin Against Oxidative Stress and Mitochondrial Dysfunction in Endothelial Cells, NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, vol.30 no.6 pp.1032-1043, 2020 |
| 2019 | 欧秀中(Ou, Hsiu-Chung)、Wan-Ching Chou、Pei-Ming Chu、Pei-Ling Hsieh、洪菁霞(Ching-Hsia Hung)、蔡昆霖(Kun-Ling Tsai)*, Fucoxanthin Protects against oxLDL-Induced Endothelial Damage via Activating the AMPK-Akt-CREB-PGC1α Pathway, MOLECULAR NUTRITION & FOOD RESEARCH, 2019 |
| 2019 | Pandey S(Pandey S)*, Luteolin: a natural flavonoid enhances the longevity of HUVECs against oxidative stress by modulating AMPK/PKC pathway., The American journal of Chinese medicine, vol.47 no.3 pp.541-557, 2019 |
| 2019 | 欧秀中、Wan-Ching Chou、洪菁霞(Ching-Hsia Hung)、朱培铭(Pei-Ming Chu)、谢珮伶(Pei-Ling Hsieh)、Shih-Hung Chan、蔡昆霖(Kun-Ling Tsai)*, Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway, ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2019 |
| 2019 | Lu CH(Lu CH)*、Shen CY、Hsieh DJ、Lee CY、Chang RL、Ju DT、白培英(Pai PY)、Viswanadha VP、欧秀中(Ou Hsiu-Chung)、黄志扬(Huang CY), Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts., Journal of applied physiology, vol.127 no.2 pp.356-364, 2019 |
| 2018 | Tsai KL(Tsai KL)*, Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells. Mol Nutr Food Res, IRISH JOURNAL OF AGRICULTURAL AND FOOD RESEARCH, vol.62 no.11 pp.e1700928-, 2018 |
| 2018 | 蔡昆霖(Tsai, Kun-Ling)、洪菁霞(Hung, Ching-Hsia)、詹世鸿(Chan, Shih-Hung)、谢佩伶(Hsieh, Pei-Ling)、欧秀中(Ou, Hsiu-Chung)、郑咏馨(Cheng, Yung-Hsin)、朱培铭(Chu, Pei-Ming)*, Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells, MOLECULAR NUTRITION & FOOD RESEARCH, vol.62 no.11 pp.e1700928-, 2018 |
| 2017 | Wen SY(Wen SY)*, Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis, PLoS One, vol.12 no.6 pp.e1709492-, 2017 |
| 2017 | Huang YT(Huang YT)*, Diallyl trisulfide & diallyl disulfide ameliorate cardiac dysfunction by suppressing apoptotic and enhancing survival pathways in experimental diabetic rats., PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.3 pp.402-410, 2017 |
| 2017 | Wen SY(Wen SY)*, Viswanadha VP, Kuo WW, Huang CY. Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis. PLoS One., PLoS One, vol.12 no.6 pp.e0179492-, 2017 |
| 2014 | Lee CH,(Lee CH,)*, Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway., INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol.15 no.6 pp.10334-10349, 2014 |
| 2013 | Hsieh YL,(Hsieh YL,)*, Ginkgo biloba extract attenuates oxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism, PHYSICS OF PARTICLES AND NUCLEI, vol.114 no.2 pp.274-285, 2013 |
| 2013 | Cheng SM(Cheng SM)*, Exercise training enhances cardiac IGFI-R/PI3K/Akt and Bcl-2 family associated pro-survival pathways in streptozotocin-induced diabetic rats, INTERNATIONAL JOURNAL OF CARDIOLOGY, vol.167 no.2 pp.478-485, 2013 |
| 2012 | Lee WJ,( Lee WJ,)*, Aspirin inhibits resistin-induced endothelial dysfunction: roles of ROS and Akt/eNOS/NO signaling pathway., JOURNAL OF VASCULAR SURGERY, vol.55 no.4 pp.1104-1115, 2012 |
| 2012 | Tsai KL(Tsai KL)*, A novel mechanism of coenzyme Q10 protects against human endothelial cells from oxidative stress-induced injury by modulating NO-related pathways., JOURNAL OF VASCULAR SURGERY, vol.23 no.5 pp.458-468, 2012 |
| 2012 | Kun-Ling Tsai(Kun-Ling Tsai)*, Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway, MOLECULAR NUTRITION & FOOD RESEARCH, vol.55 no.2 pp.227-240, 2012 |
| 2011 | Chen JY(Chen JY)*, Vinorelbine-induced oxidative injury in human endothelial cells mediated by AMPK/PKC/NADPH/NF-κB pathways., BIOCHEMICAL PHARMACOLOGY, vol.674 no.2-3 pp.227-233, 2011 |
| 2011 | Tsai KL(Tsai KL)*, Green tea epigallocatechin-3-gallate (EGCG) reduced endothelial cells dysfunction and adhesion molecule expression induced by oxidized-LDL., BIOCHEMICAL PHARMACOLOGY, vol.82 no.12 pp.1807-1821, 2011 |
| 2010 | Tsai KL(Tsai KL)*, EGCG protects against oxidized LDL-induced endothelial dysfunction by inhibiting LOX-1-mediated signaling, EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, vol.108 no.6 pp.1745-1756, 2010 |
| 2007 | Hsiu-Chung Ou(Hsiu-Chung Ou)*, Protective effects of magnolol against oxidized LDL-induced cytotoxicity in endothelial cells., JOURNAL OF VASCULAR SURGERY, vol.81 no.6 pp.421-432, 2007 |
| 2006 | Sheu WH, Rosiglitazone inhibits endothelial proliferation and angiogenesis., LIFE SCIENCES, vol.2006 no.364 pp.196-204, 2006 |
| 2006 | Hsiu-Chung Ou, Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells., CLINICA CHIMICA ACTA, vol.2006 no.364 pp.196-204, 2006 |
| 2005 | Huang HM, Protective Effect of -Keto--Methyl-nValeric Acid on BV-2 Microglia under Hypoxia or Oxidative Stress, Annals of the New York Academy of Sciences, 2005 |
| 2005 | Tsai KL(Tsai KL)*, Solanum Lyratum Thumb Prevent Oxidized Low-density Lipoprotein-induced Endothelial Dysfunction., Medicine & Science in Sports & Exercise, vol.41 no.5 pp.172-, 2005 |
| 2005 | Chi-Feng Hung(Chi-Feng Hung)*, (-)Epigallocatechin-3-gallate (EGCG), a Polyphenolic Compound in Green Tea, Protetcs Against Endothelial Cells Inflammation via Oxidized LDL., JOURNAL OF CELLULAR BIOCHEMISTRY, vol.96 no.1 pp.183-197, 2005 |
| 2005 | Lee IT, Hypercholesterolemia, not metabolic syndrome, related to adhesion of monocytes to cultured endothelium in nondiabetic subjects. Metabolism., METABOLISM-CLINICAL AND EXPERIMENTAL, vol.2005 no.54 pp.1467-1471, 2005 |
| 2004 | Shen CC, Protective effect of nicotinamide on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation., JOURNAL OF BIOMEDICAL SCIENCE, vol.2004 no.11 pp.472-481, 2004 |
| 2004 | Huang HM, alpha-keto-beta-methyl- n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores., FREE RADICAL BIOLOGY AND MEDICINE, vol.2004 no.37 pp.1779-1789, 2004 |
| 2002 | Mei-Jen Wang, Silymarin protects dopaminergic neurons against lipopolysaccharide- induced neurotoxicity by inhibiting microglia activation., EUROPEAN JOURNAL OF NEUROSCIENCE, vol.2002 no.16 pp.2103-2112, 2002 |
| 2002 | Huang HM, Apolipoprotein E polymorphism in various dementias in Taiwan Chinese population., JOURNAL OF NEURAL TRANSMISSION, vol.2002 no.109 pp.1415-21, 2002 |
| 2000 | Kuo JS, Differential alteration of catecholamine release during chemical hypoxia is correlated with cell toxicity and is blocked by protein kinase C inhibitors in PC12 cells., JOURNAL OF CELLULAR BIOCHEMISTRY, vol.2000 no.79 pp.191-201, 2000 |
| 2000 | Huang HM, Amyloid beta peptide impaired carbachol but not glutamate-mediated phosphoinositide pathways in cultured rat cortical neurons, CHINESE MEDICAL JOURNAL, vol.2000 no.25 pp.303-312, 2000 |
| 2000 | Huang HM, Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons., LIFE SCIENCES, vol.2000 no.66 pp.1879-1892, 2000 |
| 发表日期 | 论文名称 |
|---|---|
| 2011.04 | 欧秀中(Hsiu-chung Ou), 2nd National Obesity Summit, Apr. 2011, Montreal, Canada |
| 2010.08 | 欧秀中(Hsiu-chung Ou), Eighth Annual Scientific Sessions: Metabolic Signaling in the Cardiovascular System, Aug. 2010, Alberta, Canada |
| 2010.04 | 欧秀中(Hsiu-chung Ou), Experimental Biology, 2010, Apr. 2010, Califonia, USA |
| 2009.05 | 蔡昆霖、欧秀中(Hsiu-chung Ou), ACSM's Annual Meeting, May. 2009, Seattle, USA |
| 2008.06 | 欧秀中(Hsiu-chung Ou), Society for Heart & Vascular Metabolism, Jun. 2008, Boston, USA |
| 计画名称 | 参与人 | 计画期间 |
|---|---|---|
| 利用细胞模式探讨人参皂?Rg3于退化性关节炎之保护效果 (ASIA-110-CMUH-11) | 欧秀中(Hsiu-chung Ou)、邱灿宏、徐玮璟 | 2021.11 ~ 2022.10 |
| 低能量电射改善化疗药物造成肌肉衰弱之效果探讨：从分子机转到动物研究 (109-2635-B-468-001) | 欧秀中(Hsiu-chung Ou)、蔡昆霖(Kun-Ling Tsai) | 2020.08 ~ 2021.07 |
| 探讨氧化压力下抗老化基因与Galetin-3交互作用保护内皮细胞凋亡与力腺体功能异常之机转 (ASIA-108-CMUH-07) | 欧秀中(Hsiu-chung Ou)、白培英(Pei-Ying Pai)、吴书毅(Shu-Yih Wu) | 2019.11 ~ 2020.10 |
| The antiatherogenic effects of sesamin in vitro and in vivo | 2009.08 ~ 2012.07 | |
| Effects of polyphenolic compounds and exercise preconditioning protect against injury in a cerebral ischemia/reperfusion model in rat | 2008.08 ~ 2009.07 | |
| Protective effect of sesamin on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation | 2007.08 ~ 2008.07 | |
| Effects of ginkgo on oxLDL-promoted interaction between monocyte and vascular endothelium: regulation of redox status, adhesion molecules, and trans-endothelial migration (National Science Council) | 2006.08 ~ 2007.07 |
| 奖项名称 | 颁奖单位 |
|---|---|
| 中国医药大学健康照护学院研究杰出奖 | 请选择 |
| 中国医药大学健康照护学院研究杰出奖 |
| 课程类别 | 课程代码 | 课程名称 | 年度 |
|---|---|---|---|
| 大学日间部 | TR300104A | 神经物理治疗实习 (二) | 111 |
| 大学日间部 | TR300035A | 神经物理治疗学(二) | 111 |
| 大学日间部 | TR300012A | 生理学 | 111 |
| 大学日间部 | TR300024A | 基础物理治疗学(二) | 111 |
| 大学日间部 | TR300025A | 基础物理治疗学实习(二) | 111 |
| 大学日间部 | TR300026A | 公共卫生学 | 111 |
| 大学日间部 | TR300044A | 物理治疗实证医学 | 111 |
| 大学日间部 | TR300046A | 神经物理治疗总论 | 111 |
| 大学日间部 | TR300053A | 临床实习(四) | 111 |
| 大学日间部 | TR300054A | 临床实习(五) | 111 |
| 大学日间部 | TR300055A | 临床实习(六) | 111 |
| 大学日间部 | TR300090A | 特殊族群运动治疗 | 111 |
| 大学日间部 | TR300093A | 临床推论与决策 | 111 |
